Studies With Leucine, β-Hydroxybutyrate and ATP Citrate Lyase Deficient Beta Cells Support the Acetoacetate Pathway of Insulin Secretion

Por MacDonald, Michael J., Hasan, Noaman M., Longacre, Melissa J.
Publicado em 2008

Mitochondrial Malic Enzyme (ME2) In Pancreatic Islets of the Human, Rat and Mouse and Clonal Insulinoma Cells: Simple Enzyme Assay For Mitochondrial Malic Enzyme 2

Por MacDonald, Michael J., Longacre, Melissa J., Kendrick, Mindy A.
Publicado em 2009

Mitochondrial Malic Enzyme 3 Is Important for Insulin Secretion in Pancreatic β-Cells

Por Hasan, Noaman M., Longacre, Melissa J., Stoker, Scott W., Kendrick, Mindy A., MacDonald, Michael J.
Publicado no Mol Endocrinol (2015)

Chronic Reduction of the Cytosolic or Mitochondrial NAD(P)-malic Enzyme Does Not Affect Insulin Secretion in a Rat Insulinoma Cell Line

Por Brown, Laura J., Longacre, Melissa J., Hasan, Noaman M., Kendrick, Mindy A., Stoker, Scott W., MacDonald, Michael J.
Publicado em 2009

Knockdown of Both Mitochondrial Isocitrate Dehydrogenase Enzymes In Pancreatic Beta Cells Inhibits Insulin Secretion

Por MacDonald, Michael J., Brown, Laura J., Longacre, Melissa J., Stoker, Scott W., Kendrick, Mindy A., Hasan, Noaman M.
Publicado em 2013

Knockdown of ATP citrate lyase in pancreatic beta cells does not inhibit insulin secretion or glucose flux and implicates the acetoacetate pathway in insulin secretion

Por El Azzouny, Mahmoud, Longacre, Melissa J., Ansari, Israr-ul H., Kennedy, Robert T., Burant, Charles F., MacDonald, Michael J.
Publicado no Mol Metab (2016)

Characterization of P4 ATPase Phospholipid Translocases (Flippases) in Human and Rat Pancreatic Beta Cells: THEIR GENE SILENCING INHIBITS INSULIN SECRETION

Por Ansari, Israr-ul H., Longacre, Melissa J., Paulusma, Coen C., Stoker, Scott W., Kendrick, Mindy A., MacDonald, Michael J.
Publicado no J Biol Chem (2015)

Impaired Anaplerosis and Insulin Secretion in Insulinoma Cells Caused by Small Interfering RNA-mediated Suppression of Pyruvate Carboxylase

Por Hasan, Noaman M., Longacre, Melissa J., Stoker, Scott W., Boonsaen, Thirajit, Jitrapakdee, Sarawut, Kendrick, Mindy A., Wallace, John C., MacDonald, Michael J.
Publicado em 2008

Lower Succinyl-CoA:3-ketoacid-CoA Transferase (SCOT) and ATP Citrate Lyase In Pancreatic Islets of A Rat Model of Type 2 Diabetes: Knockdown of SCOT Inhibits Insulin Release In Rat...

Por Hasan, Noaman M., Longacre, Melissa J., Seed Ahmed, Mohammed, Kendrick, Mindy A., Gu, Harvest, Ostenson, Claes-Goran, Fukao, Toshiyuki, MacDonald, Michael J.
Publicado em 2010

Mass spectrometry analysis shows the biosynthetic pathways supported by pyruvate carboxylase in highly invasive breast cancer cells

Por Phannasil, Phatchariya, Ansari, Israr-ul H., El Azzouny, Mahmoud, Longacre, Melissa J., Rattanapornsompong, Khanti, Burant, Charles F., MacDonald, Michael J., Jitrapakdee, Sarawut
Publicado no Biochim Biophys Acta (2016)

Characterization of Acyl-CoA Synthetase Isoforms In Pancreatic Beta Cells: Gene Silencing Shows Participation of ACSL3 and ACSL4 In Insulin Secretion

Por Ansari, Israr-ul H., Longacre, Melissa J., Stoker, Scott W., Kendrick, Mindy A., O’Neill, Lucas M., Zitur, Laura J., Fernandez, Luis A., Ntambi, James M., MacDonald, Michael J.
Publicado no Arch Biochem Biophys (2017)

Differences between Human and Rodent Pancreatic Islets: LOW PYRUVATE CARBOXYLASE, ATP CITRATE LYASE, AND PYRUVATE CARBOXYLATION AND HIGH GLUCOSE-STIMULATED ACETOACETATE IN HUMAN PA...

Por MacDonald, Michael J., Longacre, Melissa J., Stoker, Scott W., Kendrick, Mindy, Thonpho, Ansaya, Brown, Laura J., Hasan, Noaman M., Jitrapakdee, Sarawut, Fukao, Toshiyuki, Hanson, Matthew S., Fernandez, Luis A., Odorico, Jon
Publicado em 2011