Differences between Human and Rodent Pancreatic Islets: LOW PYRUVATE CARBOXYLASE, ATP CITRATE LYASE, AND PYRUVATE CARBOXYLATION AND HIGH GLUCOSE-STIMULATED ACETOACETATE IN HUMAN PANCREATIC ISLETS

Anaplerosis, the net synthesis in mitochondria of citric acid cycle intermediates, and cataplerosis, their export to the cytosol, have been shown to be important for insulin secretion in rodent beta cells. However, human islets may be different. We observed that the enzyme activity, protein level, a...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: MacDonald, Michael J., Longacre, Melissa J., Stoker, Scott W., Kendrick, Mindy, Thonpho, Ansaya, Brown, Laura J., Hasan, Noaman M., Jitrapakdee, Sarawut, Fukao, Toshiyuki, Hanson, Matthew S., Fernandez, Luis A., Odorico, Jon
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Biochemistry and Molecular Biology 2011
विषय:
Molecular Bases of Disease
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3099655/
https://ncbi.nlm.nih.gov/pubmed/21454710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.241182
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