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Characterization of P4 ATPase Phospholipid Translocases (Flippases) in Human and Rat Pancreatic Beta Cells: THEIR GENE SILENCING INHIBITS INSULIN SECRETION

The negative charge of phosphatidylserine in lipid bilayers of secretory vesicles and plasma membranes couples the domains of positively charged amino acids of secretory vesicle SNARE proteins with similar domains of plasma membrane SNARE proteins enhancing fusion of the two membranes to promote exo...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Ansari, Israr-ul H., Longacre, Melissa J., Paulusma, Coen C., Stoker, Scott W., Kendrick, Mindy A., MacDonald, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4645617/
https://ncbi.nlm.nih.gov/pubmed/26240149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.655027
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