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Mitochondrial Malic Enzyme 3 Is Important for Insulin Secretion in Pancreatic β-Cells
Pancreatic β-cells with severely knocked down cytosolic malic enzyme (ME1) and mitochondrial NAD(P) malic enzyme (ME2) show normal insulin secretion. The mitochondrial NADP malic enzyme (ME3) is very low in pancreatic β-cells, and ME3 was previously thought unimportant for insulin secretion. Using s...
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| Publicado en: | Mol Endocrinol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Endocrine Society
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4347290/ https://ncbi.nlm.nih.gov/pubmed/25594249 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2014-1249 |
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