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Studies With Leucine, β-Hydroxybutyrate and ATP Citrate Lyase Deficient Beta Cells Support the Acetoacetate Pathway of Insulin Secretion
We hypothesized that contrasting leucine with its non-metabolizable analog 2-aminobicyclo[2,2,1]heptane-2-carboxylic acid (BCH) might provide new information about metabolic pathways involved in insulin secretion. Both compounds stimulate insulin secretion by allosterically activating glutamate dehy...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2008
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2756157/ https://ncbi.nlm.nih.gov/pubmed/18439432 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2008.03.017 |
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