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Mass spectrometry analysis shows the biosynthetic pathways supported by pyruvate carboxylase in highly invasive breast cancer cells

We recently showed that the anaplerotic enzyme pyruvate carboxylase (PC) is up-regulated in human breast cancer tissue and its expression is correlated with the late stages of breast cancer and tumor size [Phannasil et al., PloS One 10, e0129848, 2015]. In the current study we showed that PC enzyme...

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Détails bibliographiques
Publié dans:Biochim Biophys Acta
Auteurs principaux: Phannasil, Phatchariya, Ansari, Israr-ul H., El Azzouny, Mahmoud, Longacre, Melissa J., Rattanapornsompong, Khanti, Burant, Charles F., MacDonald, Michael J., Jitrapakdee, Sarawut
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5243144/
https://ncbi.nlm.nih.gov/pubmed/27890529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2016.11.021
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