A Conserved Salt Bridge between Transmembrane Segments 1 and 10 Constitutes an Extracellular Gate in the Dopamine Transporter

Tekijä Pedersen, Anders V., Andreassen, Thorvald F., Loland, Claus J.
Julkaisussa J Biol Chem (2014)

A Rhodamine-Labeled Citalopram Analogue as a High-Affinity Fluorescent Probe for the Serotonin Transporter

Tekijä Zhang, Peng, Jørgensen, Trine Nygaard, Loland, Claus J., Newman, Amy Hauck
Julkaistu 2012

Neuropsychiatric disease–associated genetic variants of the dopamine transporter display heterogeneous molecular phenotypes

Tekijä Herborg, Freja, Andreassen, Thorvald F., Berlin, Frida, Loland, Claus J., Gether, Ulrik
Julkaisussa J Biol Chem (2018)

An Intracellular Interaction Network Regulates Conformational Transitions in the Dopamine Transporter

Tekijä Kniazeff, Julie, Shi, Lei, Loland, Claus J., Javitch, Jonathan A., Weinstein, Harel, Gether, Ulrik
Julkaistu 2008

Conformational Dynamics on the Extracellular Side of LeuT Controlled by Na(+) and K(+) Ions and the Protonation State of Glu(290)

Tekijä Khelashvili, George, Schmidt, Solveig Gaarde, Shi, Lei, Javitch, Jonathan A., Gether, Ulrik, Loland, Claus J., Weinstein, Harel
Julkaisussa J Biol Chem (2016)

Surface Targeting of the Dopamine Transporter Involves Discrete Epitopes in the Distal C Terminus But Does Not Require Canonical PDZ Domain Interactions

Tekijä Bjerggaard, Christian, Fog, Jacob U., Hastrup, Hanne, Madsen, Kenneth, Loland, Claus J., Javitch, Jonathan A., Gether, Ulrik
Julkaisussa J Neurosci (2004)

Steric Hindrance Mutagenesis in the Conserved Extracellular Vestibule Impedes Allosteric Binding of Antidepressants to the Serotonin Transporter

Tekijä Plenge, Per, Shi, Lei, Beuming, Thijs, Te, Jerez, Newman, Amy Hauck, Weinstein, Harel, Gether, Ulrik, Loland, Claus J.
Julkaistu 2012

Elucidation of Structural Elements for Selectivity across Monoamine Transporters: Novel 2-[(Diphenylmethyl)sulfinyl]acetamide (Modafinil) Analogues

Tekijä Okunola-Bakare, Oluyomi M., Cao, Jianjing, Kopajtic, Theresa, Katz, Jonathan L., Loland, Claus J., Shi, Lei, Newman, Amy Hauck
Julkaistu 2014

Substrate-modulated unwinding of transmembrane helices in the NSS transporter LeuT

Tekijä Merkle, Patrick S., Gotfryd, Kamil, Cuendet, Michel A., Leth-Espensen, Katrine Z., Gether, Ulrik, Loland, Claus J., Rand, Kasper D.
Julkaisussa Sci Adv (2018)

Transition metal ion FRET uncovers K(+) regulation of a neurotransmitter/sodium symporter

Tekijä Billesbølle, Christian B., Mortensen, Jonas S., Sohail, Azmat, Schmidt, Solveig G., Shi, Lei, Sitte, Harald H., Gether, Ulrik, Loland, Claus J.
Julkaisussa Nat Commun (2016)

Conformational dynamics of the human serotonin transporter during substrate and drug binding

Tekijä Möller, Ingvar R., Slivacka, Marika, Nielsen, Anne Kathrine, Rasmussen, Søren G. F., Gether, Ulrik, Loland, Claus J., Rand, Kasper D.
Julkaisussa Nat Commun (2019)

Substrate-induced conformational dynamics of the dopamine transporter

Tekijä Nielsen, Anne Kathrine, Möller, Ingvar R., Wang, Yong, Rasmussen, Søren G. F., Lindorff-Larsen, Kresten, Rand, Kasper D., Loland, Claus J.
Julkaisussa Nat Commun (2019)

The mechanism of a high-affinity allosteric inhibitor of the serotonin transporter

Tekijä Plenge, Per, Abramyan, Ara M., Sørensen, Gunnar, Mørk, Arne, Weikop, Pia, Gether, Ulrik, Bang-Andersen, Benny, Shi, Lei, Loland, Claus J.
Julkaisussa Nat Commun (2020)

The binding sites for benztropines and dopamine in the dopamine transporter overlap

Tekijä Bisgaard, Heidi, Larsen, M. Andreas B., Mazier, Sonia, Beuming, Thijs, Newman, Amy Hauck, Weinstein, Harel, Shi, Lei, Loland, Claus J., Gether, Ulrik
Julkaistu 2010

A class of rigid linker-bearing glucosides for membrane protein structural study

Tekijä Sadaf, Aiman, Mortensen, Jonas S., Capaldi, Stefano, Tikhonova, Elena, Hariharan, Parameswaran, Ribeiro, Orquidea, Loland, Claus J., Guan, Lan, Byrne, Bernadette, Chae, Pil Seok
Julkaisussa Chem Sci (2016)

Tandem neopentyl glycol maltosides (TNMs) for membrane protein stabilisation()

Tekijä Bae, Hyoung Eun, Mortensen, Jonas S., Ribeiro, Orquidea, Du, Yang, Ehsan, Muhammad, Kobilka, Brian K., Loland, Claus J., Byrne, Bernadette, Chae, Pil Seok
Julkaisussa Chem Commun (Camb) (2016)

Butane-1,2,3,4-tetraol-based amphiphilic stereoisomers for membrane protein study: importance of chirality in the linker region

Tekijä Das, Manabendra, Du, Yang, Mortensen, Jonas S., Ribeiro, Orquidea, Hariharan, Parameswaran, Guan, Lan, Loland, Claus J., Kobilka, Brian K., Byrne, Bernadette, Chae, Pil Seok
Julkaisussa Chem Sci (2017)

Mechanism of the Association between Na(+) Binding and Conformations at the Intracellular Gate in Neurotransmitter:Sodium Symporters

Tekijä Stolzenberg, Sebastian, Quick, Matthias, Zhao, Chunfeng, Gotfryd, Kamil, Khelashvili, George, Gether, Ulrik, Loland, Claus J., Javitch, Jonathan A., Noskov, Sergei, Weinstein, Harel, Shi, Lei
Julkaisussa J Biol Chem (2015)

Rationally engineered tandem facial amphiphiles for improved membrane protein stabilization efficacy

Tekijä Das, Manabendra, Du, Yang, Mortensen, Jonas S., Hariharan, Parameswaran, Lee, Hyun Sung, Byrne, Bernadette, Loland, Claus J., Guan, Lan, Kobilka, Brian K., Chae, Pil Seok
Julkaisussa Chembiochem (2018)

Novel Xylene-linked Maltoside Amphiphiles (XMAs) for Membrane Protein Stabilisation

Tekijä Cho, Kyung Ho, Du, Yang, Scull, Nicola J, Hariharan, Parameswaran, Gotfryd, Kamil, Loland, Claus J, Guan, Lan, Byrne, Bernadette, Kobilka, Brian K, Chae, Pil Seok
Julkaisussa Chemistry (2015)