Mechanism of the Association between Na(+) Binding and Conformations at the Intracellular Gate in Neurotransmitter:Sodium Symporters

Neurotransmitter:sodium symporters (NSSs) terminate neurotransmission by Na(+)-dependent reuptake of released neurotransmitters. Previous studies suggested that Na(+)-binding reconfigures dynamically coupled structural elements in an allosteric interaction network (AIN) responsible for function-rela...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Main Authors: Stolzenberg, Sebastian, Quick, Matthias, Zhao, Chunfeng, Gotfryd, Kamil, Khelashvili, George, Gether, Ulrik, Loland, Claus J., Javitch, Jonathan A., Noskov, Sergei, Weinstein, Harel, Shi, Lei
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Molecular Biophysics
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4447972/
https://ncbi.nlm.nih.gov/pubmed/25869126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.625343
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