Direct assessment of substrate binding to the Neurotransmitter:Sodium Symporter LeuT by solid state NMR

The Neurotransmitter:Sodium Symporters (NSSs) represent an important class of proteins mediating sodium-dependent uptake of neurotransmitters from the extracellular space. The substrate binding stoichiometry of the bacterial NSS protein, LeuT, and thus the principal transport mechanism, has been hea...

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Udgivet i:eLife
Main Authors: Erlendsson, Simon, Gotfryd, Kamil, Larsen, Flemming Hofmann, Mortensen, Jonas Sigurd, Geiger, Michel-Andreas, van Rossum, Barth-Jan, Oschkinat, Hartmut, Gether, Ulrik, Teilum, Kaare, Loland, Claus J
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2017
Fag:
Biophysics and Structural Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5262378/
https://ncbi.nlm.nih.gov/pubmed/28117663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.19314
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