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Elucidation of Structural Elements for Selectivity across Monoamine Transporters: Novel 2-[(Diphenylmethyl)sulfinyl]acetamide (Modafinil) Analogues

[Image: see text] 2-[(Diphenylmethyl)sulfinyl]acetamide (modafinil, (±)-1) is a unique dopamine uptake inhibitor that binds the dopamine transporter (DAT) differently than cocaine and may have potential for the treatment of psychostimulant abuse. To further investigate structural requirements for th...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Okunola-Bakare, Oluyomi M., Cao, Jianjing, Kopajtic, Theresa, Katz, Jonathan L., Loland, Claus J., Shi, Lei, Newman, Amy Hauck
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Chemical Society 2014
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3954497/
https://ncbi.nlm.nih.gov/pubmed/24494745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm401754x
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