Elucidation of Structural Elements for Selectivity across Monoamine Transporters: Novel 2-[(Diphenylmethyl)sulfinyl]acetamide (Modafinil) Analogues

[Image: see text] 2-[(Diphenylmethyl)sulfinyl]acetamide (modafinil, (±)-1) is a unique dopamine uptake inhibitor that binds the dopamine transporter (DAT) differently than cocaine and may have potential for the treatment of psychostimulant abuse. To further investigate structural requirements for th...

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Hlavní autoři: Okunola-Bakare, Oluyomi M., Cao, Jianjing, Kopajtic, Theresa, Katz, Jonathan L., Loland, Claus J., Shi, Lei, Newman, Amy Hauck
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2014
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3954497/
https://ncbi.nlm.nih.gov/pubmed/24494745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm401754x
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