Novel and High Affinity 2-[(Diphenylmethyl)sulfinyl]acetamide (Modafinil) Analogues as Atypical Dopamine Transporter Inhibitors

The development of pharmacotherapeutic treatments of psychostimulant abuse has remained a challenge, despite significant efforts made towards relevant mechanistic targets, such as the dopamine transporter (DAT). The atypical DAT inhibitors have received attention due to their promising pharmacologic...

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Udgivet i:J Med Chem
Main Authors: Cao, Jianjing, Slack, Rachel D., Bakare, Oluyomi M., Burzynski, Caitlin, Rais, Rana, Slusher, Barbara S., Kopajtic, Theresa, Bonifazi, Alessandro, Ellenberger, Michael P., Yano, Hideaki, He, Yi, Bi, Guo-Hua, Xi, Zheng-Xiong, Loland, Claus J., Newman, Amy Hauck
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5161041/
https://ncbi.nlm.nih.gov/pubmed/27933960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.6b01373
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