R-MODAFINIL (ARMODAFINIL): A UNIQUE DOPAMINE UPTAKE INHIBITOR AND POTENTIAL MEDICATION FOR PSYCHOSTIMULANT ABUSE

BACKGROUND: (±)-Modafinil has piqued interest as a treatment for ADHD and stimulant dependence. The R-enantiomer of modafinil may have unique pharmacological properties that should be further investigated. METHODS: (±)-Modafinil and its R-(−)- and S-(+)-enantiomers were synthesized and tested for in...

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Detalhes bibliográficos
Main Authors: Loland, Claus J., Mereu, Maddalena, Okunola, Oluyomi M., Cao, J., Prisinzano, Thomas E., Mazier, Sonia, Kopajtic, Theresa, Shi, Lei, Katz, Jonathan L., Tanda, Gianluigi, Newman, Amy Hauck
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3413742/
https://ncbi.nlm.nih.gov/pubmed/22537794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2012.03.022
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