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Using click chemistry toward novel 1,2,3-triazole-linked dopamine D3 receptor ligands

The dopamine D3 receptor (D3R) is a target of pharmacotherapeutic interest in a variety of neurological disorders including schizophrenia, Parkinson's disease, restless leg syndrome, and drug addiction. A common molecular template used in the development of D3R-selective antagonists and partial...

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Détails bibliographiques
Publié dans:Bioorg Med Chem
Auteurs principaux: Keck, Thomas M., Banala, Ashwini K., Slack, Rachel D., Burzynski, Caitlin, Bonifazi, Alessandro, Okunola-Bakare, Oluyomi M., Moore, Martin, Deschamps, Jeffrey R., Rais, Rana, Slusher, Barbara S., Newman, Amy Hauck
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4468002/
https://ncbi.nlm.nih.gov/pubmed/25650314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2015.01.017
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