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Beyond small molecule SAR – using the dopamine D3 receptor crystal structure to guide drug design
The dopamine D3 receptor is a target of pharmacotherapeutic interest in a variety of neurological disorders including schizophrenia, restless leg syndrome, and drug addiction. The high protein sequence homology between the D3 and D2 receptors has posed a challenge to developing D3 receptor-selective...
Gorde:
| Argitaratua izan da: | Adv Pharmacol |
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| Egile Nagusiak: | , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2014
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4924533/ https://ncbi.nlm.nih.gov/pubmed/24484980 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/B978-0-12-420118-7.00007-X |
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