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Comparative Structure-Activity Relationships of Benztropine Analogues at the Dopamine Transporter and Histamine H(1) Receptors

Benztropine (BZT) and its analogues inhibit dopamine uptake and bind with moderate to high affinity to the dopamine transporter (DAT). However, many of these compounds, in contrast to other monoamine uptake inhibitors, lack cocaine-like behavioral effects and fail to potentiate the effects of cocain...

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Detalhes bibliográficos
Main Authors: Kulkarni, Santosh S., Kopajtic, Theresa A., Katz, Jonathan L., Newman, Amy Hauck
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1555624/
https://ncbi.nlm.nih.gov/pubmed/16460947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2006.01.017
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