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The binding sites for benztropines and dopamine in the dopamine transporter overlap
Analogues of benztropines (BZTs) are potent inhibitors of the dopamine transporter (DAT) but are less effective than cocaine as behavioral stimulants. As a result, there have been efforts to evaluate these compounds as leads for potential medication for cocaine addiction. Here we use computational m...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3703859/ https://ncbi.nlm.nih.gov/pubmed/20816875 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2010.08.021 |
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