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An Intracellular Interaction Network Regulates Conformational Transitions in the Dopamine Transporter

Neurotransmitter:sodium symporters (NSS)(1) mediate sodium-dependent reuptake of neurotransmitters from the synaptic cleft and are targets for many psychoactive drugs. The crystal structure of the prokaryotic NSS protein, LeuT, was recently solved at high resolution; however, the mechanistic details...

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Detalhes bibliográficos
Main Authors: Kniazeff, Julie, Shi, Lei, Loland, Claus J., Javitch, Jonathan A., Weinstein, Harel, Gether, Ulrik
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2427322/
https://ncbi.nlm.nih.gov/pubmed/18426798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800475200
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