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The binding sites for benztropines and dopamine in the dopamine transporter overlap
Analogues of benztropines (BZTs) are potent inhibitors of the dopamine transporter (DAT) but are less effective than cocaine as behavioral stimulants. As a result, there have been efforts to evaluate these compounds as leads for potential medication for cocaine addiction. Here we use computational m...
में बचाया:
| मुख्य लेखकों: | , , , , , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2010
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3703859/ https://ncbi.nlm.nih.gov/pubmed/20816875 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2010.08.021 |
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