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Butane-1,2,3,4-tetraol-based amphiphilic stereoisomers for membrane protein study: importance of chirality in the linker region

Amphiphile selection is a crucial step in membrane protein structural and functional study. As conventional detergents have limited scope and utility, novel agents with enhanced efficacy need to be developed. Although a large number of novel agents have been reported, so far there has been no system...

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Bibliographic Details
Published in:Chem Sci
Main Authors: Das, Manabendra, Du, Yang, Mortensen, Jonas S., Ribeiro, Orquidea, Hariharan, Parameswaran, Guan, Lan, Loland, Claus J., Kobilka, Brian K., Byrne, Bernadette, Chae, Pil Seok
Format: Artigo
Language:Inglês
Published: Royal Society of Chemistry 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5369527/
https://ncbi.nlm.nih.gov/pubmed/28451257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6sc02981g
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