Mesitylene-Cored Glucoside Amphiphiles (MGAs) for Membrane Protein Studies: Importance of Alkyl Chain Density in Detergent Efficacy

Detergents serve as useful tools for membrane protein structural and functional studies. Their amphipathic nature allows detergents to associate with the hydrophobic regions of membrane proteins whilst maintaining the proteins in aqueous solution. However, widely used conventional detergents are lim...

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Bibliographic Details
Published in:Chemistry
Main Authors: Cho, Kyung Ho, Ribeiro, Orquidea, Du, Yang, Tikhonova, Elena, Mortensen, Jonas S., Markham, Kelsey, Hariharan, Parameswaran, Loland, Claus J., Guan, Lan, Kobilka, Brian K., Byrne, Bernadette, Chae, Pil Seok
Format: Artigo
Language:Inglês
Published: 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5500206/
https://ncbi.nlm.nih.gov/pubmed/27743406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201603338
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