Mesitylene-Cored Glucoside Amphiphiles (MGAs) for Membrane Protein Studies: Importance of Alkyl Chain Density in Detergent Efficacy

Detergents serve as useful tools for membrane protein structural and functional studies. Their amphipathic nature allows detergents to associate with the hydrophobic regions of membrane proteins whilst maintaining the proteins in aqueous solution. However, widely used conventional detergents are lim...

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Veröffentlicht in:Chemistry
Hauptverfasser: Cho, Kyung Ho, Ribeiro, Orquidea, Du, Yang, Tikhonova, Elena, Mortensen, Jonas S., Markham, Kelsey, Hariharan, Parameswaran, Loland, Claus J., Guan, Lan, Kobilka, Brian K., Byrne, Bernadette, Chae, Pil Seok
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5500206/
https://ncbi.nlm.nih.gov/pubmed/27743406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201603338
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