Isomeric Detergent Comparison for Membrane Protein Stability: Importance of Inter-Alkyl-Chain Distance and Alkyl Chain Length

Membrane proteins encapsulated by detergent micelles are widely used for structural study. Because of their amphipathic property, detergents have the ability to maintain protein solubility and stability in an aqueous medium. However, conventional detergents have serious limitations in their scope an...

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Pubblicato in:Chembiochem
Autori principali: Cho, Kyung Ho, Hariharan, Parameswaran, Mortensen, Jonas S., Du, Yang, Nielsen, Anne K., Byrne, Bernadette, Kobilka, Brian K., Loland, Claus J., Guan, Lan, Chae, Pil Seok
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5500196/
https://ncbi.nlm.nih.gov/pubmed/27981750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201600429
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