Pendant-bearing glucose-neopentyl glycol (P-GNG) amphiphiles for membrane protein manipulation: Importance of detergent pendant chain for protein stabilization

Glucoside detergents are successfully used for membrane protein crystallization mainly because of their ability to form small protein-detergent complexes. In a previous study, we introduced glucose neopentyl glycol (GNG) amphiphiles with a branched diglucoside structure that has facilitated high res...

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Pubblicato in:Acta Biomater
Autori principali: Bae, Hyoung Eun, Cecchetti, Cristina, Du, Yang, Katsube, Satoshi, Mortensen, Jonas S., Huang, Weijiao, Rehan, Shahid, Lee, Ho Jin, Loland, Claus J., Guan, Lan, Kobilka, Brian K., Byrne, Bernadette, Chae, Pil Seok
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7366829/
https://ncbi.nlm.nih.gov/pubmed/32522715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2020.06.001
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