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Glucose-Neopentyl Glycol (GNG) Amphiphiles for Membrane Protein Solubilization, Stabilization and Crystallization

The development of a new class of surfactants for membrane protein manipulation, “GNG amphiphiles”, is reported. These amphiphiles display promising behavior for membrane proteins, as demonstrated recently by the high resolution structure of a sodium-pumping pyrophosphatase reported by Kellosalo et...

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Detalhes bibliográficos
Main Authors: Chae, Pil Seok, Rana, Rohini R., Gotfryd, Kamil, Rasmussen, Søren G. F., Kruse, Andrew C., Cho, Kyung Ho, Capaldi, Stefano, Carlsson, Emil, Kobilka, Brian, Loland, Claus J., Gether, Ulrik, Banerjee, Surajit, Byrne, Bernadette, Lee, John K., Gellman, Samuel H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3578972/
https://ncbi.nlm.nih.gov/pubmed/23165475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c2cc36844g
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