Pendant-bearing glucose-neopentyl glycol (P-GNG) amphiphiles for membrane protein manipulation: Importance of detergent pendant chain for protein stabilization

Glucoside detergents are successfully used for membrane protein crystallization mainly because of their ability to form small protein-detergent complexes. In a previous study, we introduced glucose neopentyl glycol (GNG) amphiphiles with a branched diglucoside structure that has facilitated high res...

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Veröffentlicht in:Acta Biomater
Hauptverfasser: Bae, Hyoung Eun, Cecchetti, Cristina, Du, Yang, Katsube, Satoshi, Mortensen, Jonas S., Huang, Weijiao, Rehan, Shahid, Lee, Ho Jin, Loland, Claus J., Guan, Lan, Kobilka, Brian K., Byrne, Bernadette, Chae, Pil Seok
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7366829/
https://ncbi.nlm.nih.gov/pubmed/32522715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2020.06.001
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