Organ-Specific Autoimmune Disease: A Deficiency of Tolerogenic Stimulation

Por Lesage, Sylvie, Goodnow, Christopher C.
Publicado em 2001

Revisiting the Prominent Anti-Tumoral Potential of Pre-mNK Cells

Por Guimont-Desrochers, Fanny, Lesage, Sylvie
Publicado em 2013

Immunoregulatory CD4(-)CD8(-) T cells as a potential therapeutic tool for transplantation, autoimmunity, and cancer

Por Hillhouse, Erin E., Delisle, Jean-Sébastien, Lesage, Sylvie
Publicado em 2013

Determination of the Relative Cell Surface and Total Expression of Recombinant Ion Channels Using Flow Cytometry

Por Bourdin, Benoîte, Segura, Emilie, Tétreault, Marie-Philippe, Lesage, Sylvie, Parent, Lucie
Publicado no J Vis Exp (2016)

Genetic characterization of interferon-producing killer dendritic cells

Por Guimont-Desrochers, Fanny, Cappello, Zachary John, Chagnon, Miguel, McDuffie, Marcia, Lesage, Sylvie
Publicado em 2009

Functional Characterization of Ca(V)α2δ Mutations Associated with Sudden Cardiac Death

Por Bourdin, Benoîte, Shakeri, Behzad, Tétreault, Marie-Philippe, Sauvé, Rémy, Lesage, Sylvie, Parent, Lucie
Publicado no J Biol Chem (2015)

The importance of dendritic cells in maintaining immune tolerance

Por Audiger, Cindy, Rahman, M. Jubayer, Yun, Tae Jin, Tarbell, Kristin V., Lesage, Sylvie
Publicado no J Immunol (2017)

Failure to Censor Forbidden Clones of CD4 T Cells in Autoimmune Diabetes

Por Lesage, Sylvie, Hartley, Suzanne B., Akkaraju, Srinivas, Wilson, Judith, Townsend, Michelle, Goodnow, Christopher C.
Publicado em 2002

A ZAP-70 kinase domain variant prevents thymocyte-positive selection despite signalling CD69 induction

Por Siggs, Owen M, Yates, Adèle L, Schlenner, Susan, Liston, Adrian, Lesage, Sylvie, Goodnow, Christopher C
Publicado em 2014

Identification of Glycosylation Sites Essential for Surface Expression of the Ca(V)α2δ1 Subunit and Modulation of the Cardiac Ca(V)1.2 Channel Activity

Por Tétreault, Marie-Philippe, Bourdin, Benoîte, Briot, Julie, Segura, Emilie, Lesage, Sylvie, Fiset, Céline, Parent, Lucie
Publicado no J Biol Chem (2016)

Genes Outside the Major Histocompatibility Complex Locus Are Linked to the Development of Thyroid Autoantibodies and Thyroiditis in NOD.H2(h4) Mice

Por McLachlan, Sandra M., Lesage, Sylvie, Collin, Roxanne, Banuelos, Bianca, Aliesky, Holly A., Rapoport, Basil
Publicado no Endocrinology (2017)

Unusual selection and peripheral homeostasis for immunoregulatory CD4(−) CD8(−) T cells

Por Dugas, Véronique, Chabot-Roy, Geneviève, Beauchamp, Claudine, Guimont-Desrochers, Fanny, Hillhouse, Erin E, Liston, Adrian, Lesage, Sylvie
Publicado em 2013

Specific Activation of the Cysteine Protease CPP32 during the Negative Selection of T Cells in the Thymus

Por Alam, Antoine, Braun, Michel Y., Hartgers, Franca, Lesage, Sylvie, Cohen, Luchino, Hugo, Patrice, Denis, François, Sékaly, Rafick-Pierre
Publicado em 1997

IL23R (Interleukin 23 Receptor) Variants Protective against Inflammatory Bowel Diseases (IBD) Display Loss of Function due to Impaired Protein Stability and Intracellular Trafficki...

Por Sivanesan, Durga, Beauchamp, Claudine, Quinou, Christiane, Lee, Jonathan, Lesage, Sylvie, Chemtob, Sylvain, Rioux, John D., Michnick, Stephen W.
Publicado no J Biol Chem (2016)

Expression of the self-marker CD47 on dendritic cells governs their trafficking to secondary lymphoid organs

Por Van, Vu Quang, Lesage, Sylvie, Bouguermouh, Salim, Gautier, Patrick, Rubio, Manuel, Levesque, Martin, Nguyen, Sébastien, Galibert, Laurent, Sarfati, Marika
Publicado em 2006

Nearby Construction Impedes the Progression to Overt Autoimmune Diabetes in NOD Mice

Por Hillhouse, Erin E., Collin, Roxanne, Chabot-Roy, Geneviève, Guyon, Marie-Josée, Tessier, Nathalie, Boulay, Maryse, Liscourt, Patricia, Lesage, Sylvie
Publicado em 2013

Evidence that MHC I-E dampens thyroid autoantibodies and prevents spreading to a second thyroid autoantigen in I-A(k) NOD mice

Por Pelletier, Adam-Nicolas, Aliesky, Holly A., Banuelos, Bianca, Chabot-Roy, Geneviève, Rapoport, Basil, Lesage, Sylvie, McLachlan, Sandra M
Publicado no Genes Immun (2015)

Mechanism of insulin resistance in a rat model of kidney disease and the risk of developing type 2 diabetes

Por Dion, François, Dumayne, Christopher, Henley, Nathalie, Beauchemin, Stéphanie, Arias, Edward B., Leblond, François A., Lesage, Sylvie, Lefrançois, Stéphane, Cartee, Gregory D., Pichette, Vincent
Publicado no PLoS One (2017)

Gene Dosage–limiting Role of Aire in Thymic Expression, Clonal Deletion, and Organ-specific Autoimmunity

Por Liston, Adrian, Gray, Daniel H.D., Lesage, Sylvie, Fletcher, Anne L., Wilson, Judith, Webster, Kylie E., Scott, Hamish S., Boyd, Richard L., Peltonen, Leena, Goodnow, Christopher C.
Publicado em 2004

The Dichotomous Pattern of IL-12R and IL-23R Expression Elucidates the Role of IL-12 and IL-23 in Inflammation

Por Chognard, Gaëlle, Bellemare, Lisa, Pelletier, Adam-Nicolas, Dominguez-Punaro, Maria C., Beauchamp, Claudine, Guyon, Marie-Josée, Charron, Guy, Morin, Nicolas, Sivanesan, Durga, Kuchroo, Vijay, Xavier, Ramnik, Michnick, Stephen W., Chemtob, Sylvain, Rioux, John D., Lesage, Sylvie
Publicado em 2014