Evidence that MHC I-E dampens thyroid autoantibodies and prevents spreading to a second thyroid autoantigen in I-A(k) NOD mice

NOD.H2(k) and NOD.H2(h4) mice carry the MHC class II molecule I-A(k) associated with susceptibility to experimentally-induced thyroiditis. Dietary iodine enhanced spontaneous thyroid autoimmunity, well known in NOD.H2(h4) mice, has not been investigated in NOD.H2(k) mice. We compared NOD.H2(h4) and...

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Detalhes bibliográficos
Publicado no:Genes Immun
Main Authors: Pelletier, Adam-Nicolas, Aliesky, Holly A., Banuelos, Bianca, Chabot-Roy, Geneviève, Rapoport, Basil, Lesage, Sylvie, McLachlan, Sandra M
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4457582/
https://ncbi.nlm.nih.gov/pubmed/25811933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gene.2015.7
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