Genes Outside the Major Histocompatibility Complex Locus Are Linked to the Development of Thyroid Autoantibodies and Thyroiditis in NOD.H2(h4) Mice

Thyroiditis and autoantibodies to thyroglobulin (TgAb) and thyroid peroxidase (TPOAb) develop spontaneously in NOD.H2(h4) mice, a phenotype enhanced by dietary iodine. NOD.H2(h4) mice were derived by introducing the major histocompatibility class (MHC) molecule I-A(k) from B10.A(4R) mice to nonobese...

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Detalhes bibliográficos
Publicado no:Endocrinology
Main Authors: McLachlan, Sandra M., Lesage, Sylvie, Collin, Roxanne, Banuelos, Bianca, Aliesky, Holly A., Rapoport, Basil
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2017
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5460802/
https://ncbi.nlm.nih.gov/pubmed/28323998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2016-1875
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