Genes Outside the Major Histocompatibility Complex Locus Are Linked to the Development of Thyroid Autoantibodies and Thyroiditis in NOD.H2(h4) Mice

Thyroiditis and autoantibodies to thyroglobulin (TgAb) and thyroid peroxidase (TPOAb) develop spontaneously in NOD.H2(h4) mice, a phenotype enhanced by dietary iodine. NOD.H2(h4) mice were derived by introducing the major histocompatibility class (MHC) molecule I-A(k) from B10.A(4R) mice to nonobese...

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Bibliografiska uppgifter
I publikationen:Endocrinology
Huvudupphovsmän: McLachlan, Sandra M., Lesage, Sylvie, Collin, Roxanne, Banuelos, Bianca, Aliesky, Holly A., Rapoport, Basil
Materialtyp: Artigo
Språk:Inglês
Publicerad: Endocrine Society 2017
Ämnen:
Research Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5460802/
https://ncbi.nlm.nih.gov/pubmed/28323998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2016-1875
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