Antibodies to Thyroid Peroxidase Arise Spontaneously with Age in NOD.H-2h4 Mice and Appear after Thyroglobulin Antibodies

Hashimoto’s thyroiditis, a common autoimmune disease, is associated with autoantibodies to thyroglobulin (Tg) and thyroid peroxidase (TPO). TPO, unlike abundant and easily purified Tg, is rarely investigated as an autoantigen in animals. We asked whether antibodies (Abs) develop to both TPO and Tg i...

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Autori principali: Chen, Chun-Rong, Hamidi, Sepehr, Braley-Mullen, Helen, Nagayama, Yuji, Bresee, Catherine, Aliesky, Holly A., Rapoport, Basil, McLachlan, Sandra M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Endocrine Society 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940509/
https://ncbi.nlm.nih.gov/pubmed/20573721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2010-0321
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