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To reflect human autoimmune thyroiditis, thyroid peroxidase (not thyroglobulin) antibodies should be measured in female (not sex‐independent) NOD.H2(h4) mice
NOD.H2(h4) mice are the most commonly used model for human autoimmune thyroiditis. Because thyroid autoimmunity develops slowly (over months), NOD.H2(h4) mice are usually exposed to excess dietary iodide to accelerate and amplify the process. However, unlike the female bias in human thyroid autoimmu...
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| Publicado no: | Clin Exp Immunol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6422661/ https://ncbi.nlm.nih.gov/pubmed/30566234 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.13249 |
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