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To reflect human autoimmune thyroiditis, thyroid peroxidase (not thyroglobulin) antibodies should be measured in female (not sex‐independent) NOD.H2(h4) mice

NOD.H2(h4) mice are the most commonly used model for human autoimmune thyroiditis. Because thyroid autoimmunity develops slowly (over months), NOD.H2(h4) mice are usually exposed to excess dietary iodide to accelerate and amplify the process. However, unlike the female bias in human thyroid autoimmu...

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Bibliografski detalji
Izdano u:Clin Exp Immunol
Glavni autori: McLachlan, S. M., Aliesky, H. A., Rapoport, B.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6422661/
https://ncbi.nlm.nih.gov/pubmed/30566234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.13249
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