Involvement of the central nervous system in acute lymphoblastic leukemia: opinions on molecular mechanisms and clinical implications based on recent data

gan Lenk, Lennart, Alsadeq, Ameera, Schewe, Denis M.
Cyhoeddwyd yn Cancer Metastasis Rev (2020)

When the bond breaks – targeting adhesion of leukemia cells to the meninges

gan Lenk, Lennart, Vogiatzi, Fotini, Schewe, Denis M.
Cyhoeddwyd yn Haematologica (2020)

The anti-oxidative transcription factor Nuclear factor E2 related factor-2 (Nrf2) counteracts TGF-β1 mediated growth inhibition of pancreatic ductal epithelial cells -Nrf2 as deter...

gan Genrich, Geeske, Kruppa, Marcus, Lenk, Lennart, Helm, Ole, Broich, Anna, Freitag-Wolf, Sandra, Röcken, Christoph, Sipos, Bence, Schäfer, Heiner, Sebens, Susanne
Cyhoeddwyd yn BMC Cancer (2016)

Larotrectinib in TRK fusion–positive pediatric B-cell acute lymphoblastic leukemia

gan Schewe, Denis M., Lenk, Lennart, Vogiatzi, Fotini, Winterberg, Dorothee, Rademacher, Annika V., Buchmann, Swantje, Henry, Dahlia, Bergmann, Anke K., Cario, Gunnar, Cox, Michael C.
Cyhoeddwyd yn Blood Adv (2019)

Proteinase-activated receptor 2 (PAR(2)) in hepatic stellate cells – evidence for a role in hepatocellular carcinoma growth in vivo

gan Mußbach, Franziska, Ungefroren, Hendrik, Günther, Bernd, Katenkamp, Kathrin, Henklein, Petra, Westermann, Martin, Settmacher, Utz, Lenk, Lennart, Sebens, Susanne, Müller, Jörg P., Böhmer, Frank-Dietmar, Kaufmann, Roland
Cyhoeddwyd yn Mol Cancer (2016)

The Hepatic Microenvironment and TRAIL-R2 Impact Outgrowth of Liver Metastases in Pancreatic Cancer after Surgical Resection

gan Miarka, Lauritz, Hauser, Charlotte, Helm, Ole, Holdhof, Dörthe, Beckinger, Silje, Egberts, Jan-Hendrik, Gundlach, Jan-Paul, Lenk, Lennart, Rahn, Sascha, Mikulits, Wolfgang, Trauzold, Anna, Sebens, Susanne
Cyhoeddwyd yn Cancers (Basel) (2019)

CD4(+) T cells potently induce epithelial-mesenchymal-transition in premalignant and malignant pancreatic ductal epithelial cells–novel implications of CD4(+) T cells in pancreatic...

gan Goebel, Lisa, Grage-Griebenow, Evelin, Gorys, Artur, Helm, Ole, Genrich, Geeske, Lenk, Lennart, Wesch, Daniela, Ungefroren, Hendrik, Freitag-Wolf, Sandra, Sipos, Bence, Röcken, Christoph, Schäfer, Heiner, Sebens, Susanne
Cyhoeddwyd yn Oncoimmunology (2015)

Engineering of CD19 Antibodies: A CD19-TRAIL Fusion Construct Specifically Induces Apoptosis in B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL) Cells In Vivo

gan Winterberg, Dorothee, Lenk, Lennart, Oßwald, Maren, Vogiatzi, Fotini, Gehlert, Carina Lynn, Frielitz, Fabian-Simon, Klausz, Katja, Rösner, Thies, Valerius, Thomas, Trauzold, Anna, Peipp, Matthias, Kellner, Christian, Schewe, Denis Martin
Cyhoeddwyd yn J Clin Med (2021)

The role of constitutive activation of FMS-related tyrosine kinase-3 and NRas/KRas mutational status in infants with KMT2A-rearranged acute lymphoblastic leukemia

gan Fedders, Henning, Alsadeq, Ameera, Schmäh, Juliane, Vogiatzi, Fotini, Zimmermann, Martin, Möricke, Anja, Lenk, Lennart, zur Stadt, Udo, Horstmann, Martin A., Pieters, Rob, Schrappe, Martin, Stanulla, Martin, Cario, Gunnar, Schewe, Denis M.
Cyhoeddwyd yn Haematologica (2017)

Liver metastasis of pancreatic cancer: the hepatic microenvironment impacts differentiation and self-renewal capacity of pancreatic ductal epithelial cells

gan Knaack, Hendrike, Lenk, Lennart, Philipp, Lisa-Marie, Miarka, Lauritz, Rahn, Sascha, Viol, Fabrice, Hauser, Charlotte, Egberts, Jan-Hendrik, Gundlach, Jan-Paul, Will, Olga, Tiwari, Sanjay, Mikulits, Wolfgang, Schumacher, Udo, Hengstler, Jan G., Sebens, Susanne
Cyhoeddwyd yn Oncotarget (2018)

IL7R is associated with CNS infiltration and relapse in pediatric B-cell precursor acute lymphoblastic leukemia

gan Alsadeq, Ameera, Lenk, Lennart, Vadakumchery, Anila, Cousins, Antony, Vokuhl, Christian, Khadour, Ahmad, Vogiatzi, Fotini, Seyfried, Felix, Meyer, Lueder-Hinrich, Cario, Gunnar, Hobeika, Elias, Debatin, Klaus-Michael, Halsey, Christina, Schrappe, Martin, Schewe, Denis M., Jumaa, Hassan
Cyhoeddwyd yn Blood (2018)

The hepatic microenvironment essentially determines tumor cell dormancy and metastatic outgrowth of pancreatic ductal adenocarcinoma

gan Lenk, Lennart, Pein, Maren, Will, Olga, Gomez, Beatriz, Viol, Fabrice, Hauser, Charlotte, Egberts, Jan-Hendrik, Gundlach, Jan-Paul, Helm, Ole, Tiwari, Sanjay, Weiskirchen, Ralf, Rose-John, Stefan, Röcken, Christoph, Mikulits, Wolfgang, Wenzel, Patrick, Schneider, Günter, Saur, Dieter, Schäfer, Heiner, Sebens, Susanne
Cyhoeddwyd yn Oncoimmunology (2017)

Synergism between IL7R and CXCR4 drives BCR-ABL induced transformation in Philadelphia chromosome-positive acute lymphoblastic leukemia

gan Abdelrasoul, Hend, Vadakumchery, Anila, Werner, Markus, Lenk, Lennart, Khadour, Ahmad, Young, Marc, El Ayoubi, Omar, Vogiatzi, Fotini, Krämer, Markus, Schmid, Vera, Chen, Zhengshan, Yousafzai, Yasar, Cario, Gunnar, Schrappe, Martin, Müschen, Markus, Halsey, Christina, Mulaw, Medhanie A., Schewe, Denis M., Hobeika, Elias, Alsadeq, Ameera, Jumaa, Hassan
Cyhoeddwyd yn Nat Commun (2020)

CD79a promotes CNS-infiltration and leukemia engraftment in pediatric B-cell precursor acute lymphoblastic leukemia

gan Lenk, Lennart, Carlet, Michela, Vogiatzi, Fotini, Spory, Lea, Winterberg, Dorothee, Cousins, Antony, Vossen-Gajcy, Michaela, Ibruli, Olta, Vokuhl, Christian, Cario, Gunnar, El Ayoubi, Omar, Kramer, Lisa, Ritgen, Matthias, Brüggemann, Monika, Häsler, Robert, Schrappe, Martin, Fuhrmann, Stephan, Halsey, Christina, Jeremias, Irmela, Hobeika, Elias, Jumaa, Hassan, Alsadeq, Ameera, Schewe, Denis M.
Cyhoeddwyd yn Commun Biol (2021)

Epithelial RNase H2 Maintains Genome Integrity and Prevents Intestinal Tumorigenesis in Mice

gan Aden, Konrad, Bartsch, Kareen, Dahl, Joseph, Reijns, Martin A.M., Esser, Daniela, Sheibani-Tezerji, Raheleh, Sinha, Anupam, Wottawa, Felix, Ito, Go, Mishra, Neha, Knittler, Katharina, Burkholder, Adam, Welz, Lina, van Es, Johan, Tran, Florian, Lipinski, Simone, Kakavand, Nassim, Boeger, Christine, Lucius, Ralph, von Schoenfels, Witigo, Schafmayer, Clemens, Lenk, Lennart, Chalaris, Athena, Clevers, Hans, Röcken, Christoph, Kaleta, Christoph, Rose-John, Stefan, Schreiber, Stefan, Kunkel, Thomas, Rabe, Björn, Rosenstiel, Philip
Cyhoeddwyd yn Gastroenterology (2019)