TGF-β Signaling in Cancer: Control by Negative Regulators and Crosstalk with Proinflammatory and Fibrogenic Pathways

por Ungefroren, Hendrik
Publicado no Cancers (Basel) (2019)

Autocrine TGF-β in Cancer: Review of the Literature and Caveats in Experimental Analysis

por Ungefroren, Hendrik
Publicado no Int J Mol Sci (2021)

The Ratio of RAC1B to RAC1 Expression in Breast Cancer Cell Lines as a Determinant of Epithelial/Mesenchymal Differentiation and Migratory Potential

por Eiden, Caroline, Ungefroren, Hendrik
Publicado no Cells (2021)

Negative Control of Cell Migration by Rac1b in Highly Metastatic Pancreatic Cancer Cells Is Mediated by Sequential Induction of Nonactivated Smad3 and Biglycan

por Otterbein, Hannah, Lehnert, Hendrik, Ungefroren, Hendrik
Publicado no Cancers (Basel) (2019)

Transfection of Peripheral Blood Monocytes with SOX2 Enhances Multipotency, Proliferation, and Redifferentiation into Neohepatocytes and Insulin-Producing Cells

por Hyder, Ayman, Ehnert, Sabrina, Fändrich, Fred, Ungefroren, Hendrik
Publicado no Stem Cells Int (2018)

RAC1B: A Rho GTPase with Versatile Functions in Malignant Transformation and Tumor Progression

por Melzer, Catharina, Hass, Ralf, Lehnert, Hendrik, Ungefroren, Hendrik
Publicado no Cells (2019)

Potential Role of MSC/Cancer Cell Fusion and EMT for Breast Cancer Stem Cell Formation

por Hass, Ralf, von der Ohe, Juliane, Ungefroren, Hendrik
Publicado no Cancers (Basel) (2019)

RAC1B: A Guardian of the Epithelial Phenotype and Protector Against Epithelial-Mesenchymal Transition

por Zinn, Rabea, Otterbein, Hannah, Lehnert, Hendrik, Ungefroren, Hendrik
Publicado no Cells (2019)

The Intimate Relationship among EMT, MET and TME: A T(ransdifferentiation) E(nhancing) M(ix) to Be Exploited for Therapeutic Purposes

por Hass, Ralf, von der Ohe, Juliane, Ungefroren, Hendrik
Publicado no Cancers (Basel) (2020)

Impact of the Tumor Microenvironment on Tumor Heterogeneity and Consequences for Cancer Cell Plasticity and Stemness

por Hass, Ralf, von der Ohe, Juliane, Ungefroren, Hendrik
Publicado no Cancers (Basel) (2020)

Interaction of tumor cells with the microenvironment

por Ungefroren, Hendrik, Sebens, Susanne, Seidl, Daniel, Lehnert, Hendrik, Hass, Ralf
Publicado em 2011

TGF-β-Dependent Growth Arrest and Cell Migration in Benign and Malignant Breast Epithelial Cells Are Antagonistically Controlled by Rac1 and Rac1b

por Melzer, Catharina, von der Ohe, Juliane, Hass, Ralf, Ungefroren, Hendrik
Publicado no Int J Mol Sci (2017)

Proteinase-activated receptors (PARs) – focus on receptor-receptor-interactions and their physiological and pathophysiological impact

por Gieseler, Frank, Ungefroren, Hendrik, Settmacher, Utz, Hollenberg, Morley D, Kaufmann, Roland
Publicado em 2013

Differential roles of Smad2 and Smad3 in the regulation of TGF-β1-mediated growth inhibition and cell migration in pancreatic ductal adenocarcinoma cells: control by Rac1

por Ungefroren, Hendrik, Groth, Stephanie, Sebens, Susanne, Lehnert, Hendrik, Gieseler, Frank, Fändrich, Fred
Publicado em 2011

Cancer stem cell niche models and contribution by mesenchymal stroma/stem cells

por Melzer, Catharina, von der Ohe, Juliane, Lehnert, Hendrik, Ungefroren, Hendrik, Hass, Ralf
Publicado no Mol Cancer (2017)

The role of TGF-β and its crosstalk with RAC1/RAC1b signaling in breast and pancreas carcinoma

por Melzer, Catharina, Hass, Ralf, von der Ohe, Juliane, Lehnert, Hendrik, Ungefroren, Hendrik
Publicado no Cell Commun Signal (2017)

Changes in uPA, PAI-1, and TGF-β Production during Breast Cancer Cell Interaction with Human Mesenchymal Stroma/Stem-Like Cells (MSC)

por Melzer, Catharina, von der Ohe, Juliane, Otterbein, Hannah, Ungefroren, Hendrik, Hass, Ralf
Publicado no Int J Mol Sci (2019)

The Small GTPase RAC1B: A Potent Negative Regulator of-and Useful Tool to Study-TGFβ Signaling

por Ungefroren, Hendrik, Wellner, Ulrich F., Keck, Tobias, Lehnert, Hendrik, Marquardt, Jens-Uwe
Publicado no Cancers (Basel) (2020)

EGF and HB-EGF enhance the proliferation of programmable cells of monocytic origin (PCMO) through activation of MEK/ERK signaling and improve differentiation of PCMO-derived hepato...

por Hyder, Ayman, Ehnert, Sabrina, Hinz, Hebke, Nüssler, Andreas K, Fändrich, Fred, Ungefroren, Hendrik
Publicado em 2012

Signaling Crosstalk of TGF-β/ALK5 and PAR2/PAR1: A Complex Regulatory Network Controlling Fibrosis and Cancer

por Ungefroren, Hendrik, Gieseler, Frank, Kaufmann, Roland, Settmacher, Utz, Lehnert, Hendrik, Rauch, Bernhard H.
Publicado no Int J Mol Sci (2018)