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RAC1B: A Rho GTPase with Versatile Functions in Malignant Transformation and Tumor Progression
RAC1B is an alternatively spliced isoform of the monomeric GTPase RAC1. It differs from RAC1 by a 19 amino acid in frame insertion, termed exon 3b, resulting in an accelerated GDP/GTP-exchange and an impaired GTP-hydrolysis. Although RAC1B has been ascribed several protumorigenic functions such as c...
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| Опубликовано в: : | Cells |
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| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
MDPI
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6356296/ https://ncbi.nlm.nih.gov/pubmed/30621237 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8010021 |
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