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TGF-β Signaling in Cancer: Control by Negative Regulators and Crosstalk with Proinflammatory and Fibrogenic Pathways

The transforming growth factor-β (TGF-β) family of secreted growth factors controls many aspects of cell and tissue physiology in multicellular eukaryotes. Dysregulation of its pathway contributes to a broad variety of pathologies, including fibrosis and cancer. TGF-β acts as a powerful tumor suppre...

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Bibliografski detalji
Izdano u:Cancers (Basel)
Glavni autor: Ungefroren, Hendrik
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6468838/
https://ncbi.nlm.nih.gov/pubmed/30893848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11030384
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