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Involvement of the central nervous system in acute lymphoblastic leukemia: opinions on molecular mechanisms and clinical implications based on recent data

Acute lymphoblastic leukemia (ALL) is the most common childhood cancer. One of the major clinical challenges is adequate diagnosis and treatment of central nervous system (CNS) involvement in this disease. Intriguingly, there is little solid evidence on the mechanisms sustaining CNS disease in ALL....

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Detalhes bibliográficos
Publicado no:Cancer Metastasis Rev
Main Authors: Lenk, Lennart, Alsadeq, Ameera, Schewe, Denis M.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7098933/
https://ncbi.nlm.nih.gov/pubmed/31970588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10555-020-09848-z
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