Endogenous nitric oxide synthase inhibitors in the biology of disease: markers, mediators and regulators?

di Caplin, Ben, Leiper, James
Pubblicazione 2012

S-nitrosylation of dimethylarginine dimethylaminohydrolase regulates enzyme activity: Further interactions between nitric oxide synthase and dimethylarginine dimethylaminohydrolase

di Leiper, James, Murray-Rust, Judith, McDonald, Neil, Vallance, Patrick
Pubblicazione 2002

Evidence for a protective role for the rs805305 single nucleotide polymorphism of dimethylarginine dimethylaminohydrolase 2 (DDAH2) in septic shock through the regulation of DDAH a...

di Lambden, Simon, Tomlinson, James, Piper, Sophie, Gordon, Anthony C., Leiper, James
Pubblicato in Crit Care (2018)

Effects of ADMA upon Gene Expression: An Insight into the Pathophysiological Significance of Raised Plasma ADMA

di Smith, Caroline L, Anthony, Shelagh, Hubank, Mike, Leiper, James M, Vallance, Patrick
Pubblicazione 2005

Modulation of Rac1 Activity by ADMA/DDAH Regulates Pulmonary Endothelial Barrier Function

di Wojciak-Stothard, Beata, Torondel, Belen, Zhao, Lan, Renné, Thomas, Leiper, James M.
Pubblicazione 2009

Regulation of the ADMA-DDAH system in endothelial cells: a novel mechanism for the sterol response element binding proteins, SREBP1c and -2

di Ivashchenko, Christine Y., Bradley, Benjamin T., Ao, Zhaohui, Leiper, James, Vallance, Patrick, Johns, Douglas G.
Pubblicazione 2010

ADMA: A Key Player in the Relationship between Vascular Dysfunction and Inflammation in Atherosclerosis

di Dowsett, Laura, Higgins, Erin, Alanazi, Sarah, Alshuwayer, Noha A., Leiper, Fiona C., Leiper, James
Pubblicato in J Clin Med (2020)

Regulation of fluid reabsorption in rat or mouse proximal renal tubules by asymmetric dimethylarginine and dimethylarginine dimethylaminohydrolase 1

di Bell, Tracy, Araujo, Magali, Luo, Zaiming, Tomlinson, James, Leiper, James, Welch, William J., Wilcox, Christopher S.
Pubblicato in Am J Physiol Renal Physiol (2018)

Mechanistic Interactions of Uromodulin with the Thick Ascending Limb: Perspectives in Physiology and Hypertension

di Boder, Philipp, Mary, Sheon, Mark, Patrick B., Leiper, James, Dominiczak, Anna F., Padmanabhan, Sandosh, Rampoldi, Luca, Delles, Christian
Pubblicato in J Hypertens (2021)

An Unexpected Effect of Proton Pump Inhibitors: Elevation of the Cardiovascular Risk Factor ADMA

di Ghebremariam, Yohannes T., LePendu, Paea, Lee, Jerry C., Erlanson, Daniel A., Slaviero, Anna, Shah, Nigam H., Leiper, James, Cooke, John P.
Pubblicazione 2013

Proton Pump Inhibitors and Cardiovascular Risk

di Ghebremariam, Yohannes T., LePendu, Paea, Lee, Jerry C., Erlanson, Daniel A., Slaviero, Anna, Shah, Nigam H., Leiper, James M., Cooke, John P.
Pubblicazione 2014

Dimethylarginine dimethylaminohydrolase 1 is involved in spinal nociceptive plasticity

di D'Mello, Richard, Sand, Claire A., Pezet, Sophie, Leiper, James M., Gaurilcikaite, Egle, McMahon, Stephen B., Dickenson, Anthony H., Nandi, Manasi
Pubblicato in Pain (2015)

Overexpression of GTP Cyclohydrolase 1 Feedback Regulatory Protein Is Protective in a Murine Model of Septic Shock

di Starr, Anna, Sand, Claire A., Heikal, Lamia, Kelly, Peter D., Spina, Domenico, Crabtree, Mark, Channon, Keith M., Leiper, James M., Nandi, Manasi
Pubblicato in Shock (2014)

NRF2 prevents hypertension, increased ADMA, microvascular oxidative stress, and dysfunction in mice with two weeks of ANG II infusion

di Wang, Cheng, Luo, Zaiming, Carter, Gabriella, Wellstein, Anton, Jose, Pedro A., Tomlinson, James, Leiper, James, Welch, William J., Wilcox, Christopher S., Wang, Dan
Pubblicato in Am J Physiol Regul Integr Comp Physiol (2018)

nNOS-Expressing Neurons in the Ventral Tegmental Area and Substantia Nigra Pars Compacta

di Paul, Eleanor J., Kalk, Eliza, Tossell, Kyoko, Irvine, Elaine E., Franks, Nicholas P., Wisden, William, Withers, Dominic J., Leiper, James, Ungless, Mark A.
Pubblicato in eNeuro (2018)

Dimethylarginine dimethylaminohydrolase-2 deficiency promotes vascular regeneration and attenuates pathological angiogenesis

di Lange, Clemens, Mowat, Freya, Sayed, Haroon, Mehad, Manjit, Duluc, Lucie, Piper, Sophie, Luhmann, Ulrich, Nandi, Manasi, Kelly, Peter, Smith, Alexander, Ali, Robin, Leiper, James, Bainbridge, James
Pubblicato in Exp Eye Res (2016)

Role of asymmetric methylarginine and connexin 43 in the regulation of pulmonary endothelial function

di Tsang, Hilda, Leiper, James, Hou Lao, Ka, Dowsett, Laura, Delahaye, Matthew W., Barnes, Gareth, Wharton, John, Howard, Luke, Iannone, Lucio, Lang, Ninian N., Wilkins, Martin R., Wojciak-Stothard, Beata
Pubblicazione 2013

A Novel Pathway for Metabolism of the Cardiovascular Risk Factor Homoarginine by alanine:glyoxylate aminotransferase 2

di Rodionov, Roman N., Oppici, Elisa, Martens-Lobenhoffer, Jens, Jarzebska, Natalia, Brilloff, Silke, Burdin, Dmitrii, Demyanov, Anton, Kolouschek, Anne, Leiper, James, Maas, Renke, Cellini, Barbara, Weiss, Norbert, Bode-Böger, Stefanie M.
Pubblicato in Sci Rep (2016)

Metabolomic profiling of amines in sepsis predicts changes in NOS canonical pathways

di Tesfai, Abel, MacCallum, Niall, Kirkby, Nicholas S., Gashaw, Hime, Gray, Nicola, Want, Elizabeth, Quinlan, Gregory J., Mumby, Sharon, Leiper, James M., Paul-Clark, Mark, Ahmetaj-Shala, Blerina, Mitchell, Jane A.
Pubblicato in PLoS One (2017)

Evidence That Links Loss of Cyclooxygenase-2 With Increased Asymmetric Dimethylarginine: Novel Explanation of Cardiovascular Side Effects Associated With Anti-Inflammatory Drugs

di Ahmetaj-Shala, Blerina, Kirkby, Nicholas S., Knowles, Rebecca, Al’Yamani, Malak, Mazi, Sarah, Wang, Zhen, Tucker, Arthur T., Mackenzie, Louise, Armstrong, Paul C. J., Nüsing, Rolf M., Tomlinson, James A. P., Warner, Timothy D., Leiper, James, Mitchell, Jane A.
Pubblicato in Circulation (2015)