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Dimethylarginine dimethylaminohydrolase-2 deficiency promotes vascular regeneration and attenuates pathological angiogenesis

Ischemia-induced angiogenesis is critical for tissue repair, but aberrant neovascularization in the retina causes severe sight impairment. Nitric oxide (NO) has been implicated in neovascular eye disease because of its pro-angiogenic properties in the retina. Nitric oxide production is inhibited end...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Exp Eye Res
Hauptverfasser: Lange, Clemens, Mowat, Freya, Sayed, Haroon, Mehad, Manjit, Duluc, Lucie, Piper, Sophie, Luhmann, Ulrich, Nandi, Manasi, Kelly, Peter, Smith, Alexander, Ali, Robin, Leiper, James, Bainbridge, James
Format: Artigo
Sprache:Inglês
Veröffentlicht: Academic Press 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4912010/
https://ncbi.nlm.nih.gov/pubmed/27181226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2016.05.007
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