Dimethylarginine dimethylaminohydrolase-2 deficiency promotes vascular regeneration and attenuates pathological angiogenesis

Ischemia-induced angiogenesis is critical for tissue repair, but aberrant neovascularization in the retina causes severe sight impairment. Nitric oxide (NO) has been implicated in neovascular eye disease because of its pro-angiogenic properties in the retina. Nitric oxide production is inhibited end...

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Udgivet i:Exp Eye Res
Main Authors: Lange, Clemens, Mowat, Freya, Sayed, Haroon, Mehad, Manjit, Duluc, Lucie, Piper, Sophie, Luhmann, Ulrich, Nandi, Manasi, Kelly, Peter, Smith, Alexander, Ali, Robin, Leiper, James, Bainbridge, James
Format: Artigo
Sprog:Inglês
Udgivet: Academic Press 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4912010/
https://ncbi.nlm.nih.gov/pubmed/27181226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2016.05.007
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