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Dimethylarginine dimethylaminohydrolase I enhances tumour growth and angiogenesis

Angiogenesis is a prerequisite for tumour progression and is highly regulated by growth factors and cytokines a number of which also stimulate the production of nitric oxide. Asymmetric dimethylarginine is an endogenous inhibitor of nitric oxide synthesis. Asymmetric dimethylarginine is metabolised...

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Detalhes bibliográficos
Main Authors: Kostourou, V, Robinson, S P, Cartwright, J E, Whitley, G St J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2364234/
https://ncbi.nlm.nih.gov/pubmed/12237779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600518
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