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S-nitrosylation of dimethylarginine dimethylaminohydrolase regulates enzyme activity: Further interactions between nitric oxide synthase and dimethylarginine dimethylaminohydrolase

The enzyme dimethylarginine dimethylaminohydrolase (DDAH) hydrolyses asymmetrically methylated arginine residues that are endogenously produced inhibitors of nitric oxide synthases (NOS). We and others have proposed that DDAH activity is a key determinant of intracellular methylarginine concentratio...

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Autors principals: Leiper, James, Murray-Rust, Judith, McDonald, Neil, Vallance, Patrick
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC129707/
https://ncbi.nlm.nih.gov/pubmed/12370443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.212269799
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