Dimethylarginine dimethylaminohydrolase 1 is involved in spinal nociceptive plasticity

Activation of neuronal nitric oxide synthase, and consequent production of nitric oxide (NO), contributes to spinal hyperexcitability and enhanced pain sensation. All NOS isoforms are inhibited endogenously by asymmetric dimethylarginine, which itself is metabolised by dimethylarginine dimethylamino...

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Vydáno v:Pain
Hlavní autoři: D'Mello, Richard, Sand, Claire A., Pezet, Sophie, Leiper, James M., Gaurilcikaite, Egle, McMahon, Stephen B., Dickenson, Anthony H., Nandi, Manasi
Médium: Artigo
Jazyk:Inglês
Vydáno: Wolters Kluwer 2015
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4770343/
https://ncbi.nlm.nih.gov/pubmed/26098438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/j.pain.0000000000000269
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