Perturbing PSD-95 Interactions With NR2B-subtype Receptors Attenuates Spinal Nociceptive Plasticity and Neuropathic Pain

Peripheral inflammation or nerve injury induces a primary afferent barrage into the spinal cord, which can cause N-methyl -aspartate (NMDA) receptor-dependent alterations in the responses of dorsal horn sensory neurons to subsequent afferent inputs. This plasticity, such as “wind-up” and central sen...

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Autori principali: D'Mello, Richard, Marchand, Fabien, Pezet, Sophie, McMahon, Stephen B, Dickenson, Anthony H
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2011
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3188755/
https://ncbi.nlm.nih.gov/pubmed/21427709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.42
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