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Modulation of Rac1 Activity by ADMA/DDAH Regulates Pulmonary Endothelial Barrier Function
Endogenously produced nitric oxide synthase inhibitor, asymmetric methylarginine (ADMA) is associated with vascular dysfunction and endothelial leakage. We studied the role of ADMA, and the enzymes metabolizing it, dimethylarginine dimethylaminohydrolases (DDAH) in the regulation of endothelial barr...
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| Principais autores: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Cell Biology
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2613095/ https://ncbi.nlm.nih.gov/pubmed/18923147 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-04-0395 |
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