NRF2 prevents hypertension, increased ADMA, microvascular oxidative stress, and dysfunction in mice with two weeks of ANG II infusion

Nuclear factor erythyroid factor 2 (Nrf2) transcribes genes in cultured endothelial cells that reduce reactive oxygen species (ROS) and generate nitric oxide (NO) or metabolize asymmetric dimethylarginine (ADMA), which inhibits NO synthase (NOS). Therefore, we undertook a functional study to test th...

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Vydáno v:Am J Physiol Regul Integr Comp Physiol
Hlavní autoři: Wang, Cheng, Luo, Zaiming, Carter, Gabriella, Wellstein, Anton, Jose, Pedro A., Tomlinson, James, Leiper, James, Welch, William J., Wilcox, Christopher S., Wang, Dan
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2018
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5899246/
https://ncbi.nlm.nih.gov/pubmed/29167164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00122.2017
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