Changing Faces in Virology: The Dutch Shift from Oncogenic to Oncolytic Viruses

Por Belcaid, Zineb, Lamfers, Martine L.M., van Beusechem, Victor W., Hoeben, Rob C.
Publicado em 2014

Establishing the Lysine-rich Protein CEST Reporter Gene as a CEST MR Imaging Detector for Oncolytic Virotherapy

Por Farrar, Christian T., Buhrman, Jason S., Liu, Guanshu, Kleijn, Anne, Lamfers, Martine L. M., McMahon, Michael T., Gilad, Assaf A., Fulci, Giulia
Publicado no Radiology (2015)

Truncating the i-leader open reading frame enhances release of human adenovirus type 5 in glioma cells

Por van den Hengel, Sanne K, de Vrij, Jeroen, Uil, Taco G, Lamfers, Martine L, Sillevis Smitt, Peter AE, Hoeben, Rob C
Publicado em 2011

Gene delivery into malignant glioma by infectivity-enhanced adenovirus: In vivo versus in vitro models

Por Van Houdt, Winan J., Wu, Hongju, Glasgow, Joel N., Lamfers, Martine L., Dirven, Clemens M., Gillespie, G. Yancey, Curiel, David T., Haviv, Yosef S.
Publicado em 2007

Anatomical Differences Determine Distribution of Adenovirus after Convection-Enhanced Delivery to the Rat Brain

Por Idema, Sander, Caretti, Viola, Lamfers, Martine L. M., van Beusechem, Victor W., Noske, David P., Vandertop, W. Peter, Dirven, Clemens M. F.
Publicado em 2011

Coronavirus Genetically Redirected to the Epidermal Growth Factor Receptor Exhibits Effective Antitumor Activity against a Malignant Glioblastoma

Por Verheije, Monique H., Lamfers, Martine L. M., Würdinger, Thomas, Grinwis, Guy C. M., Gerritsen, Winald R., van Beusechem, Victor W., Rottier, Peter J. M.
Publicado em 2009

Serum-free culture success of glial tumors is related to specific molecular profiles and expression of extracellular matrix–associated gene modules

Por Balvers, Rutger K., Kleijn, Anne, Kloezeman, Jenneke J., French, Pim J., Kremer, Andreas, van den Bent, Martin J., Dirven, Clemens M. F., Leenstra, Sieger, Lamfers, Martine L. M.
Publicado em 2013

Distinguishing inflammation from tumor and peritumoral edema by myeloperoxidase magnetic resonance imaging: Molecular MRI of intracerebral inflammation

Por Kleijn, Anne, Chen, John W., Buhrman, Jason S., Wojtkiewicz, Gregory R., Iwamoto, Yoshiko, Lamfers, Martine L., Stemmer-Rachamimov, Anat O., Rabkin, Samuel D., Weissleder, Ralph, Martuza, Robert L., Fulci, Giulia
Publicado em 2011

Locally-Delivered T-Cell-Derived Cellular Vehicles Efficiently Track and Deliver Adenovirus Delta24-RGD to Infiltrating Glioma

Por Balvers, Rutger K., Belcaid, Zineb, van den Hengel, Sanne K., Kloezeman, Jenneke, de Vrij, Jeroen, Wakimoto, Hiroaki, Hoeben, Rob C., Debets, Reno, Leenstra, Sieger, Dirven, Clemens, Lamfers, Martine L.M.
Publicado em 2014

The HDAC Inhibitors Scriptaid and LBH589 Combined with the Oncolytic Virus Delta24-RGD Exert Enhanced Anti-Tumor Efficacy in Patient-Derived Glioblastoma Cells

Por Berghauser Pont, Lotte M.E., Kleijn, Anne, Kloezeman, Jenneke J., van den Bossche, Wouter, Kaufmann, Johanna K., de Vrij, Jeroen, Leenstra, Sieger, Dirven, Clemens M.F., Lamfers, Martine L.M.
Publicado no PLoS One (2015)

The Bcl-2 inhibitor Obatoclax overcomes resistance to histone deacetylase inhibitors SAHA and LBH589 as radiosensitizers in patient-derived glioblastoma stem-like cells

Por Berghauser Pont, Lotte M.E., Spoor, Jochem K.H., Venkatesan, Subramanian, Swagemakers, Sigrid, Kloezeman, Jenneke J., Dirven, Clemens M.F., van der Spek, Peter J., Lamfers, Martine L.M., Leenstra, Sieger
Publicado no Genes Cancer (2014)

BI-28 NEW MONOCYTE SUBTYPING DISTINGUISHES GLIOMA PATIENTS FROM HEALTHY CONTROLS

Por van den Bossche, Wouter B.L., Lamfers, Martine L.M., Vincent, Arnaud J.P.E., de Bruin Versteeg, Sandra, Josiassen, Karin, Orfao, Alberto, Dirven, Clemens M.F., van Dongen, Jacques J.M.
Publicado em 2014

Efficient and Selective Gene Transfer into Primary Human Brain Tumors by Using Single-Chain Antibody-Targeted Adenoviral Vectors with Native Tropism Abolished

Por van Beusechem, Victor W., Grill, Jacques, Mastenbroek, D. C. Jeroen, Wickham, Thomas J., Roelvink, Peter W., Haisma, Hidde J., Lamfers, Martine L. M., Dirven, Clemens M. F., Pinedo, Herbert M., Gerritsen, Winald R.
Publicado em 2002

Delta-24-RGD Oncolytic Adenovirus Elicits Anti-Glioma Immunity in an Immunocompetent Mouse Model

Por Jiang, Hong, Clise-Dwyer, Karen, Ruisaard, Kathryn E., Fan, Xuejun, Tian, Weihua, Gumin, Joy, Lamfers, Martine L., Kleijn, Anne, Lang, Frederick F., Yung, Wai-Kwan Alfred, Vence, Luis M., Gomez-Manzano, Candelaria, Fueyo, Juan
Publicado em 2014

Cyclophosphamide Increases Transgene Expression Mediated by an Oncolytic Adenovirus in Glioma-Bearing Mice Monitored by Bioluminescence Imaging

Por Lamfers, Martine L. M., Fulci, Giulia, Gianni, Davide, Tang, Yi, Kurozumi, Kazuhiko, Kaur, Balveen, Moeniralm, Sharif, Saeki, Yoshinaga, Carette, Jan E., Weissleder, Ralph, Vandertop, W. Peter, van Beusechem, Victor W., Dirven, Clemens M. F., Chiocca, E. Antonio
Publicado em 2006

TM-04 A TRANSGENIC ZEBRAFISH MODEL FOR GLIOMAS WITH MUTATIONS IN ISOCITRATE DEHYDROGENASE 1

Por Gao, Ya D., van der Linde, Herma C. Z., Struys, Eduard A., van Breugel, Valeska, de Wit, Maurice, Erdem, Lale, Bovée, Judith V.M.G., Lamfers, Martine L. M., Silleviss Smitt, Peter A.E., Salomons, Gajja S., Willemsen, Rob, French, Pim J.
Publicado no Neuro Oncol (2014)

TP53 mutated glioblastoma stem-like cell cultures are sensitive to dual mTORC1/2 inhibition while resistance in TP53 wild type cultures can be overcome by combined inhibition of mT...

Por Venkatesan, Subramanian, Hoogstraat, Marlous, Caljouw, Ester, Pierson, Tessa, Spoor, Jochem K.H., Zeneyedpour, Lona, Dubbink, Hendrikus J., Dekker, Lennard J., van der Kaaij, Mariëlle, Kloezeman, Jenneke, Berghauser Pont, Lotte M.E., Besselink, Nicolle J.M., Luider, Theo M., Joore, Jos, Martens, John W., Lamfers, Martine L.M., Sleijfer, Stefan, Leenstra, Sieger
Publicado no Oncotarget (2016)

DNA methylation and somatic mutations converge on cell cycle and define similar evolutionary histories in brain tumors

Por Mazor, Tali, Pankov, Aleksandr, Johnson, Brett E., Hong, Chibo, Hamilton, Emily G., Bell, Robert J.A., Smirnov, Ivan V., Reis, Gerald F., Phillips, Joanna J., Barnes, Michael J., Idbaih, Ahmed, Alentorn, Agusti, Kloezeman, Jenneke J., Lamfers, Martine L. M., Bollen, Andrew W., Taylor, Barry S., Molinaro, Annette M., Olshen, Adam B., Chang, Susan M., Song, Jun S., Costello, Joseph F.
Publicado no Cancer Cell (2015)

Evolution of DNA repair defects during malignant progression of low-grade gliomas after temozolomide treatment

Por van Thuijl, Hinke F., Mazor, Tali, Johnson, Brett E., Fouse, Shaun D., Aihara, Koki, Hong, Chibo, Malmström, Annika, Hallbeck, Martin, Heimans, Jan J., Kloezeman, Jenneke J., Stenmark-Askmalm, Marie, Lamfers, Martine L.M., Saito, Nobuhito, Aburatani, Hiroyuki, Mukasa, Akitake, Berger, Mitchell S., Söderkvist, Peter, Taylor, Barry S., Molinaro, Annette M., Wesseling, Pieter, Reijneveld, Jaap C., Chang, Susan M., Ylstra, Bauke, Costello, Joseph F.
Publicado no Acta Neuropathol (2015)