Delta-24-RGD Oncolytic Adenovirus Elicits Anti-Glioma Immunity in an Immunocompetent Mouse Model

BACKGROUND: Emerging evidence suggests anti-cancer immunity is involved in the therapeutic effect induced by oncolytic viruses. Here we investigate the effect of Delta-24-RGD oncolytic adenovirus on innate and adaptive anti-glioma immunity. DESIGN: Mouse GL261-glioma model was set up in immunocompet...

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Autori principali: Jiang, Hong, Clise-Dwyer, Karen, Ruisaard, Kathryn E., Fan, Xuejun, Tian, Weihua, Gumin, Joy, Lamfers, Martine L., Kleijn, Anne, Lang, Frederick F., Yung, Wai-Kwan Alfred, Vence, Luis M., Gomez-Manzano, Candelaria, Fueyo, Juan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4020829/
https://ncbi.nlm.nih.gov/pubmed/24827739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0097407
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