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IT-15 DELTA-24-RGDOX: TARGETING CO-STIMULATORY IMMUNE CHECKPOINT PROTEINS WITH ONCOLYTIC ADENOVIRUSES
OX40 ligand (OX40L), the ligand for OX40 on activated CD4+ and CD8+ T cells, has adjuvant properties for establishing effective T-cell immunity against cancer. The hypothesis of this study is that oncolytic viruses expressing OX40L will stimulate tumor-specific T cells by the OX40L-OX40 engagement....
Wedi'i Gadw mewn:
| Prif Awduron: | , , , , , , , , , , , |
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| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
Oxford University Press
2014
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4218231/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou258.13 |
| Tagiau: |
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