EXTH-30. IN SITU AUTOVACCINATION MEDIATED BY ONCOLYTIC ADENOVIRUS DELTA-24-RGDOX INDUCES EFFICACIOUS IMMUNITY AGAINST METASTATIC MELANOMA

We have reported that Delta-24-RGDOX, an oncolytic adenovirus expressing the immune co-stimulator OX40 ligand (OX40L), induces efficacious anti-glioma immunity in syngeneic intracranial glioma models of immune competent mice. Here we sought to determine if the local injection of the virus triggers a...

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Bibliografische gegevens
Gepubliceerd in:Neuro Oncol
Hoofdauteurs: Jiang, Hong, Nguyen, Teresa, Ho Shi, Dong, Fan, Xuejun, Gumin, Joy, Bernatchez, Chantale, Lang, Frederick, Gomez-Manzano, Candelaria, Fueyo, Juan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6217277/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.379
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