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Oncolytic adenovirus and tumor-targeting immune modulatory therapy improve autologous cancer vaccination

Oncolytic viruses selectively lyse tumor cells, disrupt immunosuppression within the tumor and reactivate anti-tumor immunity, but they have yet to live up to their therapeutic potential. Immune checkpoint modulation has been efficacious in a variety of cancer with an immunogenic microenvironment, b...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Jiang, Hong, Rivera-Molina, Yisel, Gomez-Manzano, Candelaria, Clise-Dwyer, Karen, Bover, Laura, Vence, Luis M., Yuan, Ying, Lang, Frederick F., Toniatti, Carlo, Hossain, Mohammad B., Fueyo, Juan
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5549681/
https://ncbi.nlm.nih.gov/pubmed/28566332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-17-0468
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