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Oncolytic adenovirus research evolution: from cell-cycle checkpoints to immune checkpoints
Oncolytic adenoviruses are modified to exploit the aberrant expression of proteins in cancer cells to obtain cancer-selective replication. Moreover, the natural tropism of oncolytic adenoviruses can be redirected to tumor cells. Clinical trials revealed that oncolytic viruses showed poor replication...
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| Udgivet i: | Curr Opin Virol |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4550502/ https://ncbi.nlm.nih.gov/pubmed/25863716 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coviro.2015.03.009 |
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