Cyclophosphamide Increases Transgene Expression Mediated by an Oncolytic Adenovirus in Glioma-Bearing Mice Monitored by Bioluminescence Imaging

Approaches to improve the oncolytic potency of replication-competent adenoviruses include the insertion of therapeutic transgenes into the viral genome. Little is known about the levels and duration of in vivo transgene expression by cells infected with such “armed” viruses. Using a tumor-selective...

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Main Authors: Lamfers, Martine L. M., Fulci, Giulia, Gianni, Davide, Tang, Yi, Kurozumi, Kazuhiko, Kaur, Balveen, Moeniralm, Sharif, Saeki, Yoshinaga, Carette, Jan E., Weissleder, Ralph, Vandertop, W. Peter, van Beusechem, Victor W., Dirven, Clemens M. F., Chiocca, E. Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819149/
https://ncbi.nlm.nih.gov/pubmed/16996314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2006.08.008
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